Recent Advances in the Treatment of Peptic Ulcer


A survey of the literature dealing with recent advances in the treatment of peptic ulcer reveals a growing appreciation of the importance of the pathological physiology of this malady. In the various clinics and medical centers the gastro-enterologists are forsaking “rule of thumb” treatment and are attempting to individualize each case. The effect is that an ulcer patient is receiving more intelligent treatment than the mere prescribing of a diet and alkaline powders. Physicians are growing sensible to the fact that the most important therapeutic effort is not merely to assist in the immediate healing of the ulcer, but as far as possible, to prevent a recurrence of this lesion at a future date. It is well known that one of the most characteristic features of a peptic ulcer is its periodicity, its tendency to recur most commonly in the spring and fall of the year, often with almost symptomless remissions between these semi-yearly exacerbations of indigestion. Any treatment which fails to take into consideration these fairly rhythmic periods of reactivation will, in most instances, fail to be more than a palliative. With these facts in mind, it is the thesis of this paper to elaborate the following points: (1) the known etiological factors in the production of peptic ulcer; (2) the pathological physiology of the stomach and duodenum in ulcer cases; (3) the role of diet and drugs in the effort to restore normal function; and (4) procedures to adopt in the effort to prevent recurrence of an ulcer.



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