Urinary Tract Disorders
The following abstracts conclude the proceedings of the course on Medical and Surgical Disorders of the Urinary Tract presented by the Frank E. Bunts Educational Institute on November 17, 1949. The first portion of these proceedings appeared in the April issue of the Cleveland Clinic Quarterly.
DIETARY MANAGEMENT OF UREMIA
G. M. C. Masson, Ph.D.
A study was conducted to test experimentally the effects of high iso-caloric carbohydrate, fat, and protein diets and the effect of hormones (desoxycorticosterone acetate and free testosterone) on survival times and azotemia (blood urea N) in bilaterally nephrectomized rats. All treatment was begun at the time of nephrectomy. Survival was definitely improved and azotemia greatly diminished by administration of fat or carbohydrate rather than protein.
Treatment with hormones had no significant effect on survival time regardless of diet, and little effect on azotemia. Neither did diets nor hormones effect the evolution of uremia in nephrectomized rats subjected to simulated infection (turpentine abscess).
These experiments substantiate the beneficial effects claimed by Borst for the treatment of uremia by administration of a high caloric diet, composed largely of carbohydrate. They do not confirm the suggestions of others that hormonal treatment is of value after nephrectomy.
CYSTITIS AND INTERSTITIAL CYSTITIS
J. G. Warden, M.D.
The etiologic agents of cystitis may be grouped into 4 main classes: (1) The non-bacterial agents including both chemical and mechanical; (2) Bacterial including chronic, tuberculous, and the rarely luetic lesions; (3) Yeast fungi; (4) Animal parasites.
The symptoms are:
As a general. . .