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Long Survival of a Patient with Cerebellar Medulloblastoma and Malignant Goiter Treated by Roentgen Therapy

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Abstract

The following case report is of interest because the patient has survived eleven years following roentgen therapy for cerebellar medulloblastoma and four years following treatment for malignant adenoma of the thyroid gland.

Case Report

A woman, aged 27, was first seen at Cleveland Clinic Hospital by Dr. W. James Gardner on October 2, 1935. She was semicomatose, restless, and responded to questions only in monosyllables. She had divergent strabismus, papilledema, paresis of the left side of the face, left arm and leg, a positive Babinski sign, left patellar clonus, and bilateral ankle clonus. Laboratory examinations of blood and spinal fluid gave negative findings. The patient had no fever.

Five weeks prior to admission she had complained of attacks of frontal headaches which had increased in frequency and severity for at least a week, then changed in location to the occipital region. These attacks were associated with diplopia, vertigo, and occasional vomiting. She had given up her position as a public school music supervisor to rest in bed. Her symptoms had increased, however, and she entered a hospital and was examined by Dr. Louis J. Karnosh, who considered the diagnosis consistent with encephalomyelitis. He advised removal to Cleveland Clinic Hospital, where she was admitted in the condition described. Further questioning elicited the information that a few weeks prior to the onset of symptoms she had been struck on the head by a falling suitcase. This injury indicated the possibility of a frontal subdural hematoma.

On the third day after hospital admission. . .


 

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