Antiphospholipid antibody syndrome: Recent findings on managing this challenging condition
Mark A. Crowther, MD
Division of Hematology, McMaster University, Hamilton, Ontario
Address: Mark A. Crowther, MD, Division of Hematology, McMaster University, St. Joseph's Hospital, 50 Charlton Avenue East, Hamilton, Ontario L8N 4A6, Canada
Medical Grand Rounds articles are based on edited transcripts from Division of Medicine Grand Rounds presentations at The Cleveland Clinic Foundation. They are approved by the author but are not peer-reviewed.
ABSTRACTPatients with antiphospholipid syndrome can suffer recurrent thrombosis that is very difficult to manage. Recent research has demonstrated that high-intensity anticoagulation is not superior to standard therapy. Basic questions about the nature and treatment of this syndrome remain unanswered.