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High postpartum breast cancer metastasis risk may persist for a decade
Analysis of more than 700 patients showed that risk of metastasis was approximately twofold higher for a decade after childbirth, with risks about...
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Checkpoint inhibitors linked to rare, but serious immune-related side effects
The study breaks down the hematological immune-related side effects of checkpoint inhibitors.
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CRS/HIPEC safety concerns may be outdated
In a retrospective study of more than 34,000 patients, CRS/HIPEC had a 30-day mortality rate of 1.1%, compared with rates of 2.5%-3.9% for other...
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Dietary aluminum may trigger IBS
Aluminum ingestion triggers visceral hypersensitivity in rats, suggesting that dietary levels of aluminum may contribute to development of...
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HPV-16/-18 dramatically increases risk of high-grade CIN in young women
Women younger than 30 years who test positive for HPV-16/-18 are almost 10 times as likely to develop high-grade cervical intraepithelial...
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Biomarker algorithm may offer noninvasive look at liver fibrosis
Algorithm distinguished NAFLD patients with advanced liver fibrosis from those with mild to moderate fibrosis.
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‘Error neuron’ EEG findings could open up future clinical applications
The findings may be applied to conditions in which the important executive function task of error self-monitoring is unbalanced, such as obsessive...
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IgA vasculitis increases risks for hypertension, chronic kidney disease
Data “suggest that IgAV should not be considered a ‘single-hit’ disease.”
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Proposed neuroblastoma classification scheme hinges on telomere maintenance mechanisms
Genomic analysis showed telomere maintenance mechanisms, RAS mutations, and p53 mutations were strongly associated with outcome and other disease...
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RCC research has opened door to the future, but “much work remains to be done”
Future efforts should aim to link genetic knowledge with prognosis and treatment selection.
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hTERT expression predicts RCC survival, tumor aggressiveness
Disease-specific survival was lowest in ccRCC patients with high human telomerase reverse transcriptase protein expression.
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Age-related gene expression may affect responses to RCC therapy
Older patients with ccRCC may respond better than younger patients to phosphoinositide 3-kinase (PI3K) or checkpoint inhibition because of age-...
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Elderly NHL patients have higher NRM after HSCT
A retrospective study suggests elderly patients with non-Hodgkin lymphoma (NHL) are more likely to die, but not relapse, within a year of...
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DECLARE: Dapagliflozin improves some cardiovascular, renal outcomes
The large outcomes trial didn’t show a benefit in major adverse cardiovascular events.
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SRS beats surgery in early control of brain mets, advantage fades with time
Patients undergoing complete surgical resection for brain mets were at much higher risk of local recurrence than patients.