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Cardiovascular risk score multipliers suggested for rheumatic diseases
Guidelines could tailor cardiovascular risk scores by using a multiplier of 2.5 for systemic sclerosis, 2.0 for lupus, and 1.5 for any other...
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RA risk raised by work-related inhaled agents
Exposure to detergents, dusts, and other chemicals in the workplace could be putting genetically susceptible people at risk of rheumatoid...
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Gestational hypertension-diabetes combo signals CVD risk
Having both hypertensive disorders and diabetes while pregnant ups later cardiovascular risk, suggesting greater care is needed when these...
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Rituximab raises remission rate in granulomatosis with polyangiitis
Remission at 6 months was recorded in 73.1% of rituximab-treated patients and 40.1% of cyclophosphamide-treated patients in a multicenter target...
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52-week data show lebrikizumab atopic dermatitis effects maintained
ADvocate1 and ADvocate2 are two of several phase 3 trials evaluating the efficacy and safety of lebrikizumab for the treatment of atopic...
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Ruxolitinib repigments many vitiligo-affected body areas
Ruxolitinib is a Janus kinase 1/2 inhibitor that has been available for the treatment for atopic dermatitis for more than a year.
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BREEZE-AD-PEDS: First data for baricitinib in childhood eczema reported
Treatment with the oral JAK inhibitor was significantly more effective than placebo only with the highest dose evaluated.
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Alopecia areata: Positive results reported for two investigational JAK inhibitors
“This is truly transformative therapy,” one of the investigators, Brett King, MD, PhD, said.
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Study identifies skin biomarkers that predict newborn eczema risk
"We are able to identify predictive immune biomarkers of atopic dermatitis using a noninvasive method," the investigator said.
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Ezetimibe-statin combo lowers liver fat in open-label trial
A significant 5.8% decrease in hepatic steatosis was seen after 24 weeks’ treatment with ezetimibe and rosuvastatin comparing baseline with end of...
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Early age at hysterectomy ups type 2 diabetes risk
Having a hysterectomy appears to increase the risk of incident type 2 diabetes, particularly in younger women, and if the ovaries are removed at...
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Mothers’ diabetes linked to ADHD in their children
A small increased risk of ADHD in children born to mothers with diabetes, including pregestational diabetes and gestational diabetes, has been...
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Apremilast alleviates severe psoriasis in some children, data show
“In this randomized, placebo-controlled trial, oral apremilast demonstrated effectiveness and was well tolerated.”
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Hope shines bright for hidradenitis suppurativa treatments
Research into HS is "an incredibly active field at this moment," said Alexa B. Kimball, MD, MPH.
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Experts express caution over
type 2 diabetes/tea-drinking claim
Drinking four cups of tea a day was linked to a 17% lower risk for developing type 2 diabetes in a study, but experts warn these data are...