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ODC1 gene linked to newly described neurodevelopmental disorder
A previously undescribed neurometabolic disease has been linked to a gain-of-function mutation of the ODC1 gene.
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Study supports halting antiseizure medications after neonatal seizures
A registry study found that halting antiseizure medications after acute symptomatic neonatal seizures had similar outcomes to maintenance therapy...
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Evaluating the impact of new pediatric brain tumor classifications
Additional molecular subtypes of childhood brain tumors will have far-reaching implications for diagnosis and management.
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Acute flaccid myelitis: More likely missed than diagnosed
A retrospective series reports that 78% of children with acute flaccid myelitis are misdiagnosed initially, causing delays in treatment.
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CBD for LGS: Fewer seizures, but thrombocytopenia risk
Cannabidiol reduces seizures in Lennox Gastaut syndrome out to 3 years, but has been linked to thrombocytopenia in children also on valproic acid...
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Review finds evidence for beta-blockers for some rosacea symptoms
A systematic review provides limited evidence to support oral beta-blockers as a treatment for rosacea-associated facial erythema and flushing.
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Valvular AFib heightens risk in TAVR
A single-center study finds that valvular atrial fibrillation raises the risk for cardiovascular death after transcatheter aortic valve...
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When viruses collide: Flu season during pandemic
Seasonal flu in the midst of the COVID-19 pandemic threatens to overwhelm practitioners, hospitals and the health care system.
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Machine learning shows ability to predict diastolic dysfunction with ECG
A machine-learning model using electrocardiography data showed potential to predict left ventricle diastolic dysfunction without echocardiography...
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PVR reassessed as predictor of heart failure
A reconsideration of the accepted benchmark for pulmonary vascular hypertension as a predictor of heart failure may be warranted.
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MSBase study validates therapy for relapse in secondary progressive MS
An observational cohort study validates medical treatment to reduce disability accumulation in active secondary progressive multiple sclerosis.
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ACC panel defines, advises on heart failure with ‘recovered’ EF
An American College of Cardiology expert panel has issued a definition of heart failure with recovered ejection fraction and recommendations for...
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Most younger MI patients wouldn’t get statins under guidelines
A retrospective study shows that most younger first-time myocardial infarction patients didn’t meet guideline requirements for preventative statin...
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AHA statement addresses genetic testing for CVD
The American Heart Association issued a scientific statement that provides recommendations for conducting genetic testing for cardiovascular...