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HDL cholesterol not linked to CHD risk in Blacks: REGARDS
A large biracial cohort study found that low levels of high-density lipoprotein cholesterol don’t raise heart disease risk in Black patients.
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ACR and EULAR roll out updated antiphospholipid syndrome criteria
A joint planning group proposes updates to 16-year-old criteria for classifying antiphospholipid syndrome.
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Denosumab may halt erosive hand OA progression
In a randomized clinical trial, denosumab seemed to halt progression of erosive hand osteoarthritis, but had a delayed impact on pain.
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StopRA trial: Hydroxychloroquine doesn’t prevent or delay onset of rheumatoid arthritis
A randomized clinical trial found that hydroxychloroquine was no more effective than placebo at preventing or delaying onset of rheumatoid...
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Combination therapy shows mixed results for scleroderma-related lung disease
A study of mycophenolate mofetil alone and in combination with pirfenidone for scleroderma-related interstitial lung disease showed mixed results...
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Combination therapy may boost remission in JIA
Study shows early methotrexate plus a biologic may aid remission and disease inactivity in pediatric polyarticular juvenile idiopathic arthritis...
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Rituximab ‘a reasonable alternative to cyclophosphamide’ to improve ILD-CTD
A clinical trial found that rituximab and cyclophosphamide had similar outcomes for interstitial lung disease associated with connective tissue...
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Ten-day methotrexate pause after COVID vaccine booster enhances immunity against Omicron variant
Researchers in Germany report a 10-day post-vaccination hold on methotrexate boosts immunity against Omicron without compromising safety or risk...
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Diabetes becoming less potent risk factor for CVD events
Diabetes is no longer equal to cardiovascular disease as a risk factor for cardiovascular events, according to a population-based study in Ontario...
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COVID pandemic associated with anorexia in Canadian youth
“There was so much disruption and [so many] restrictions to young peoples’ daily routines ... That led to heightened anxiety and depression and...
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NSAIDs linked to heart failure risk in diabetes
A Danish case-crossover study found that NSAID use increased heart failure risks 50% in patients with diabetes.
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Cholesterol levels lowering in U.S., but disparities emerge
While cholesterol levels in American adults have improved overall in the past decade, disparities in control have emerged, according to a new...
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Antibiotic before oral surgery spares endocarditis; study validates guidelines
“You have to have this [antibiotic prophylaxis] conversation when you see your patient with a prosthetic valve or who’s had endocarditis every...
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Gut metabolites may explain red meat–ASCVD link
A large cohort study implicates gut microbiome metabolites as the key link between red meat consumption and atherosclerotic cardiovascular disease...
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Is prostasin a clue to diabetes/cancer link?
Elevated plasma prostasin levels may be a potential biomarker of diabetes and cancer mortality, according to a Swedish prospective, population-...