News
FDA places partial hold on trials after secondary lymphoma
A pediatric patient developed a secondary T-cell lymphoma during a phase 1 trial of tazemetostat.
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FDA approves new drug for thrombocytopenia
The oral spleen tyrosine kinase inhibitor is expected to be available in the United States in late May.
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PDPK1 could be novel target in MCL
The poor prognosis of mantle cell lymphoma despite advances in immunochemotherapy means that new therapeutic targets are needed.
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FDA grants priority review of follicular lymphoma drug
The target date for FDA action is Oct. 5, 2018.
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European Commission expands denosumab indication
Following the FDA’s lead, the European Commission approves denosumab for prevention of skeletal-related events.
News
MRD may indicate relapse risk in AML
The presence of molecular minimal residual disease, despite complete remission, could be an independent predictor of future relapse risk.
Video
VIDEO: How to prepare PTCL patients for transplant
LA JOLLA, CALIF. – Dr. Steven Horwitz says the key to preparing patients for transplant is “good remission.”
News
FDA approves nilotinib for children with CML
The decision expands the drug’s indication to include first- and second-line use in children.
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FDA approves new option in Hodgkin lymphoma treatment
The approval is based on results from the ECHELON-1 trial in previously untreated patients with stage III or IV classical Hodgkin lymphoma.
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Time to rethink MCL treatment, trial design
Dr. Leonid Yavorkovsky of Kaiser Permanente San Jose Medical Center questions the traditional approach to treatment of class mantle cell lymphoma...
News
Consider steroid-induced hypertension when treating pediatric ALL
Infants and children with secondary diabetes mellitus were among those most likely to develop steroid-induced hypertension.
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Hemophilia A treatment gains approval in Europe
Emicizumab is now approved in Europe and the United States for routine prophylaxis of bleeding episodes in people with factor VIII inhibitors.
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FDA approves tests to screen for tickborne parasite in blood supply
The two new tests will screen whole blood and plasma samples.
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Phase 2 study tests low-dose maintenance therapy for ALL
The trial is expected to enroll 40 adult ALL patients in complete remission with positive minimal residual disease.
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Gene therapy for hemophilia A gets fast-track review
The FDA has granted breakthrough therapy designation to a gene therapy product aimed at hemophilia A.
