News
Progressive myeloma after induction? Go straight to transplant
The study did not find a survival advantage for patients who had salvage therapy to deepen their responses before moving on to transplant.
News
Calquence earns breakthrough designation for CLL monotherapy
The Bruton tyrosine kinase inhibitor is already approved for the treatment of adults with mantle cell lymphoma who have received at least one...
News
Low-dose radiation therapy looks effective in hard-to-treat MCL
The treatment approach can be used safely with concurrent chemotherapy.
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ABIM rolls out shorter, tailored MOC exams in oncology
The new pathway allows oncologists to choose a focused exam in hematologic malignancies, breast cancer, or general oncology every 2 years,...
Video
Cleveland Clinic targets time to treat in cancer
CHICAGO – The Taussig Cancer Institute at the Cleveland Clinic reduced the time to treat for newly diagnosed cancer patients by 33%. Taussig’s...
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Low intensity bridging may be best path to CAR T in adult ALL
CHICAGO – Researchers examined the use of high- and low-intensity chemotherapy bridging for patients waiting for treatment with a CD19-directed...
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FDA approves PI3K inhibitor alpelisib for breast cancer
The PI3K inhibitor is approved for use with fulvestrant for HR-positive, HER2-negative, PIK3CA-mutated advanced or metastatic breast cancer in...
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Trial follow-up spotlights survival gains in follicular lymphoma
The 13-year update to the GITMO-IIL trial showed the important role of complete remission in prolonged survival. This is the longest follow-up...
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FDA approves venetoclax/obinutuzumab combo for CLL
Venetoclax/obinutuzumab was compared with venetoclax/chlorambucil in the CLL14 study and showed superior progression-free survival in previously...
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Short telomeres predict poorer response to chemo in CLL
High-throughput, single telomere–length analysis appears to be a useful tool in predicting response to FCR-based treatment among previously...
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Bendamustine-rituximab shines in frontline treatment of MCL, iNHL
Long-term follow-up data from the BRIGHT study support bendamustine plus rituximab as a frontline treatment option in mantle cell lymphoma and...
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Turoctocog alfa appears safe, effective in reducing bleeds
The phase 3b open label trial included extended use of turoctocog alfa among males of all ages with severe hemophilia A.
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Thrombin generation looks promising as a hemophilia biomarker
SAN DIEGO – Thrombin generation appears better able to differentiate between bleeding severities, compared with baseline factor activity.
News
Study identifies four patient subgroups in hemophilia A
SAN DIEGO – The Hemophilia Inhibitor PUP Study (HIPS) analyzed Factor VIII–specific antibodies in previously untreated infants with severe...
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Myeloma expert named as endowed cancer chair at Emory
News on Dr. Sagar Lonial, Dr. J. Ross Mitchell, Dr. Oren Cahlon, and the death of Dr. Bertrand Coiffier.