News
Erythema extent predicts death in cutaneous GVHD
- Author:
- M. Alexander Otto, PA, MMS
Study: Extent of skin erythema correlates with deaths from graft-versus-host disease in blood cancer patients after stem cell transplants.
News
Nicotinamide does not prevent skin cancer after organ transplant
- Author:
- M. Alexander Otto, PA, MMS
Nicotinamide (vitamin B3) has been shown to prevent nonmelanoma skin cancers in healthy, immunocompetent people, so physicians routinely prescribe...
News
Hemophilia A gene therapy under FDA review
- Author:
- M. Alexander Otto, PA, MMS
Recently published clinical data showed that a costly new gene therapy for hemophilia A was found largely durable at 2 years.
News
Strategy to reduce peritoneal metastases in gastric cancer
- Author:
- M. Alexander Otto, PA, MMS
Surgery and postoperative chemotherapy are standard of care for advanced gastric cancer, but up to half of patients develop peritoneal metastases...
News
Omit radiation in older women with low-risk, ER+ breast cancer
- Author:
- M. Alexander Otto, PA, MMS
Trial randomly assigns 1,326 women who had undergone a lumpectomy to either whole-breast irradiation or no radiation on a background of tamoxifen...
News
Docetaxel as alternative to cisplatin for H&N radiotherapy
- Author:
- M. Alexander Otto, PA, MMS
“This is the first randomized study demonstrating the benefit of an alternate radiosensitizing agent in cisplatin-ineligible patients.”
News
Key factors predict gallbladder cancer on routine cholecystectomy
- Author:
- M. Alexander Otto, PA, MMS
Identifying predictors allows surgeons to send high-risk individuals for oncologic evaluation beforehand and to prepare for intraoperative frozen...
News
‘Valid option’ for partial breast irradiation in breast cancer
- Author:
- M. Alexander Otto, PA, MMS
Study authors suggest that 30 Gy in five daily fractions is a ‘valid option’ for patients who received lumpectomy for early breast cancer.
News
FDA OKs sacituzumab govitecan for HR+ metastatic breast cancer
- Author:
- M. Alexander Otto, PA, MMS
Label expansion for the Trop-2–directed antibody-drug conjugate was based on the TROPICS-02 trial.
News
FDA OKs elacestrant for ESR1+ advanced, metastatic breast cancer
- Author:
- M. Alexander Otto, PA, MMS
The agency also approved the Guardant360 CDx assay as a companion diagnostic to identify breast cancer patients who meet the treatment...
News
Tucatinib plus trastuzumab approved for HER2+ colorectal cancer
- Author:
- M. Alexander Otto, PA, MMS
This is the first FDA-approved treatment for HER2-positive metastatic colorectal cancer.
News
Congenital CMV linked to pediatric hyperdiploid ALL
- Author:
- M. Alexander Otto, PA, MMS
Infection in some infants may alter immune function in a way that increases vulnerability to more direct causes of ALL.
News
Global effort needed to widen access to HSCT
- Author:
- M. Alexander Otto, PA, MMS
Study findings reveal “unacceptably low” access to HSCT in some regions, triggering a call to action.
News
Managing trastuzumab deruxtecan adverse events in the real world
- Author:
- M. Alexander Otto, PA, MMS
Doctor says real-world toxicity experience has been worse than clinical trial data.
News
FDA OKs teclistamab for relapsed/refractory multiple myeloma
- Author:
- M. Alexander Otto, PA, MMS
FDA has approved teclistamab as a new treatment option for heavily pretreated adults with relapsed/refractory multiple myeloma.