Article
How effective is spironolactone for treating resistant hypertension?
EVIDENCE-BASED ANSWER: Very effective. Spironolactone reduces systolic blood pressure (SBP) by 11 to 17 mm Hg and diastolic blood pressure (DBP)...
Article
What are the risks of long-term PPI use for GERD symptoms in patients > 65 years?
EVIDENCE-BASED ANSWER: The use of proton pump inhibitors (PPIs) to control gastroesophageal reflux disease (GERD) is significantly associated with...
Article
How do oral NSAIDs compare to other oral analgesics right after an acute musculoskeletal injury?
EVIDENCE-BASED ANSWER: Nonsteroidal anti-inflammatory drugs (NSAIDs) are at least as effective as other oral analgesics (opioids, acetaminophen)...