News
Zanubrutinib looks ‘robust’ in Waldenström macroglobulinemia
Phase 1 data shows a high overall response rate to the BTK inhibitor.
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Variant not linked to CLL in Southeast Europe
DUBROVNIK, CROATIA – The PTPN22 R620W polymorphism was not associated with CLL in patients from Southeast Europe.
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FDA approves elotuzumab with pom/dex in refractory myeloma
The approval is based on results from the phase 2 ELOQUENT-3 trial.
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FDA approves second pegfilgrastim biosimilar
Pegfilgrastim-cbqv, previously known as CHS-1701, will be marketed as Udenyca by Coherus BioSciences.
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Novel risk factors for febrile neutropenia in NHL, solid tumors
Corticosteroid use was most strongly associated with chemotherapy-induced febrile neutropenia.
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FDA expands approval of pembrolizumab in NSCLC
Pembrolizumab is now approved for use in combination with carboplatin and either paclitaxel or nab-paclitaxel for the first-line treatment of...
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Ruxolitinib receives priority review for acute GVHD
Ruxolitinib is under review as a treatment for patients with acute graft-versus-host disease who have had an inadequate response to...
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OMS721 gains orphan designation for HSCT-associated thrombotic microangiopathy
Early results from a phase 2 trial suggest OMS721 can be effective against HSCT-TMA.
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When to choose stem cell transplant in PTCL
DUBROVNIK, CROATIA – Dr. Ali Bazarbachi gives his tips for when to use allo- versus auto-HSCT in patients with peripheral T-cell lymphomas.
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CDK8 inhibitor shows activity against AML
DUBROVNIK, CROATIA – SEL120 looks active against acute myeloid leukemia in preclinical work, but experts aren’t sure why.
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When is it CMML?
DUBROVNIK, CROATIA – Dr. Nadira Durakovic offers her tips for differentiating between CMML and other look-alike disorders.
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FDA offers guidance on MRD assessment in blood cancer trials
The draft guidance document provides advice to industry on how to use minimal residual disease as a biomarker in clinical trials of hematologic...
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Optimizing use of TKIs in chronic leukemia
DUBROVNIK, CROATIA – Dr. Hagop M. Kantarjian offers tips for choosing the best TKI when treating patients with CML.
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Updated ThroLy system predicts need for thromboprophylaxis
DUBROVNIK, CROATIA – The revised ThroLy scoring system offers a lymphoma-specific system to predict thromboembolic events.