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Cognitive testing for older drivers: Is there a benefit?
A policy designed to weed out cognitively impaired drivers over age 75 had the unforeseen effect of exposing them to injuries incurred while...
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Dietary zinc seen reducing migraine risk
New evidence adds the mineral to a growing list of nutritional factors that can influence migraine.
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The paradox of Pompe disease
For nearly 2 decades, patients with even the most severe genetic mutations have been surviving on therapy. But clinicians must now contend with...
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NORD Rare Disease Centers of Excellence: A new network seeks to break down barriers in rare disease care
“The goal was to find places that could help with unanswered questions, whether diagnostic questions or treatment questions.”
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Smell loss may be a biomarker of Alzheimer’s disease risk
Rapidly deteriorating performance on serial smell tests not only predicted Alzheimer’s disease among cognitively normal adults, but corresponded...
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Will the headache field embrace rofecoxib?
The drug formerly known as Vioxx, withdrawn in 2004 over cardiovascular safety concerns, may be given new life as an acute treatment for migraine...
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Microbleeds, age contribute to ARIA risk with aducanumab
New safety results show that brain bleeds at baseline increase risk of brain edema, and that age contributes to risk of bleeds during treatment....
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Headache seen affecting some pregnancy outcomes
A new study links migraine – and also tension-type headache – to small-for-gestational-age babies.
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Novel gene therapy ‘reprograms’ cells to reverse neurologic deficits in children with rare disease
Months after surgery to deliver a gene therapy, children saw complete resolution of oculogyric crises, a hallmark of their disease, and were able...
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Two case reports identify Guillain-Barré variants after SARS-CoV-2 vaccination
Investigators in India and the United Kingdom describe rare presentations of Guillain-Barré syndrome marked by facial paralysis, but evidence of...
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The aducanumab revolution
As the controversial new Alzheimer’s drug makes its way from research settings to the clinic, practitioners brace for a potential sea change in...
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Basal ganglia microcircuits offer clues to Parkinson’s symptoms
In a mouse model of Parkinson’s disease, specific neuronal subpopulations, or microcircuits, in the basal ganglia could be manipulated to...
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Palliative care for patients with dementia: When to refer?
A systematic literature review finds few consistent criteria for referrals save for disease stage. Researchers argue that patients’ needs may be...
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Neurologic disorders ubiquitous and rising in the U.S.
Most of the rise in disease burden could be attributed to population aging, while age-standardized figures showed stroke and dementias to be level...
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Cognitive effects seen as transient for Alzheimer’s drug atabecestat
Follow-up data from a canceled trial showed that cognitive worsening from the BACE inhibitor was reversed within 6 months of stopping treatment....