News
New data bolster latitude’s association with MS prevalence
DALLAS – After integrating data from 94 new studies, “the latitudinal gradient in MS prevalence ... significantly enhanced in magnitude,”...
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Which comorbidities most diminish quality of life in patients with MS?
DALLAS – Systemic lupus erythematosus, depression, and hyperthyroidism may have large effects on health-related quality of life in patients with...
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Evaluations for possible MS often turn up one of its many mimics
DALLAS – At two multiple sclerosis (MS) centers, 74% of patients referred for a possible diagnosis of MS did not have the disease.
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Migraine associated with more severe disability in patients with MS
DALLAS – “Traditional migraine risk factors such as obesity, anxiety, and depression were also overrepresented in our cohort” of patients with MS...
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Incidence of treated depression nearly 100% higher in patients with MS
DALLAS – Patients with multiple sclerosis have a higher incidence of new treated depression, compared with matched patients without MS, according...
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Can technology automate assessments of patients with MS in the clinic?
DALLAS – An iPad-based series of neuroperformance tests and patient-reported outcomes may facilitate the clinical evaluation of patients with...
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Ublituximab depletes B cells in phase 2 trial
DALLAS – The investigational therapy may allow for lower doses and shorter infusion times, compared with available anti-CD20 treatments.
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CSF biomarker clusters correlate with MS severity
DALLAS – Proteins related to astrocytes and microglia are elevated in the CSF of patients with multiple sclerosis and correlate with MS disease...
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Biologic aging is associated with MS disability progression
DALLAS – Telomere length correlates with disability independent of chronological age.
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Early intensive treatment of MS may benefit patients
Real-world population-based cohort study finds better outcomes at 5 years with first-line treatment with a high-efficacy therapy.
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When to suspect a severe skin reaction to an AED
NEW ORLEANS – Although most eruptions are benign, certain symptoms raise concerns about rare and potentially fatal antiepileptic drug reactions....
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Does adherence to a Mediterranean diet reduce the risk of Parkinson’s disease?
Greater adherence to a Mediterranean diet is associated with lower probability of prodromal Parkinson’s disease, but questions about this...
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International survey probes oxygen’s efficacy for cluster headache
Oxygen is a highly effective therapy with few complications, according to a survey of patients with cluster headache.
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Novel plasma biomarkers may predict preclinical Alzheimer’s disease
The approach will need to be validated and translated “to a simpler automated platform suitable for wider utility.”
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Aerobic exercise may mitigate age-related cognitive decline
Among adults with below-average fitness, aerobic exercise significantly improves executive function, a randomized trial finds.