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Duodenoscopes contain more bacteria than expected
Additional cleaning of duodenoscopes beyond manufacturer recommendations may be needed to prevent infections.
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More data link severe sleep apnea and aggressive melanoma
The findings offer further evidence of the link between cancer and sleep-disordered breathing.
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Guideline authors inconsistently disclose conflicts
Financial conflicts are often underreported by authors of clinical practice guidelines in several specialties including gastroenterology,...
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Stroke, arterial dissection events reported with Lemtrada, FDA says
Rare but serious events described in multiple sclerosis patients given alemtuzumab (Lemtrada) prompts new warning.
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Less-distressed patients driving increase in outpatient services
Adults with less-severe distress accounted for most of a recent absolute increase in outpatient mental health services.
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Experts advise risk stratification for newborn early-onset sepsis
Risk stratification for early-onset sepsis differs for preterm and term neonates.
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Two-stage preeclampsia screening cuts cost, preserves effectiveness
The results support the effectiveness of using only certain tests paired with maternal factors to identify high-risk patients for further...
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AAP advises moderate physical, cognitive activity after sports concussion
A clinical report from the American Academy of Pediatrics counsels children to return to reduced activities post concussion versus total rest.
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USPSTF advises primary care to screen for unhealthy alcohol use
Evidence supports alcohol screening for adults, but data are insufficient for adolescents.
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FDA accepts priority review of dupilumab for adolescent atopic dermatitis
Phase 3 study results of dupilumab in patients aged 12-17 years with atopic dermatitis were submitted to the agency.
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Guideline authors inconsistently disclose conflicts
Review of payment records shows some undisclosed payments of $10,000 or more.
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FDA panels back brexanolone infusion for postpartum depression
Brexanolone infusion called a game changer by some committee members in a 17-1 vote recommending agency approval.
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Pediatric indications appear in one-third of orphan drug approvals
WASHINGTON – Many pediatric indications involve genetic disorders.
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FDA panels vote no on opioid-containing drug for MDD
The advisory panels voted 21-2 against recommending the combo drug as an add-on for refractory depression.