Article
- Author:
- Gary Kelsberg, MD
Publish date: December 12, 2022
EVIDENCE-BASED ANSWER: There are modest effects on depression but not anxiety. Gender-affirming hormone therapy (GAHT) is associated with modest i...
Article
- Author:
- Gary Kelsberg, MD
Publish date: June 22, 2021
Probably, although there are no head-to-head trials comparing the 2 dosing regimens. Event-driven pre-exposure prophylaxis (PrEP) dosing red...
Article
- Author:
- Gary Kelsberg, MD
Publish date: March 4, 2021
EVIDENCE-BASED ANSWER: Yes, to some degree—but it is of uncertain clinical significance. Over a period of 6 months, metformin modestly reduced weig...
Article
- Author:
- Gary Kelsberg, MD
Publish date: July 20, 2020
EVIDENCE-BASED ANSWER: No. Adding a proton pump inhibitor (PPI) in patients taking antiplatelet medications such as clopidogrel for acute coronary ...
Article
- Author:
- Gary Kelsberg, MD
Publish date: May 12, 2020
EVIDENCE-BASED ANSWER: Yes, to some extent it does, and primarily in patients with low vitamin D levels. Supplementation reduces asthma exacerbatio...
Article
- Author:
- Gary Kelsberg, MD
Publish date: March 4, 2020
EVIDENCE-BASED ANSWER: Possibly. No trials have directly assessed detection of melanoma and other skin cancers by primary care providers.
Article
- Author:
- Gary Kelsberg, MD
Publish date: December 9, 2019
EVIDENCE-BASED ANSWER: Probably. Electronic cigarette (e-cigarette) use by adolescents is associated with a 2- to 4-fold increase in cigarette...
Opinion
- Author:
- Gary Kelsberg, MD
Publish date: March 11, 2019
EVIDENCE-BASED ANSWER: Probably not, based on the balance of evidence. While low-quality evidence may suggest potential benefit, t...
Article
- Author:
- Gary Kelsberg, MD
Publish date: December 3, 2018
EVIDENCE-BASED ANSWER: No. Amniotomy neither shortens spontaneous labor nor improves any of the following outcomes: length of first stage of labor,...
Article
- Author:
- Gary Kelsberg, MD
Publish date: October 1, 2018
EVIDENCE-BASED ANSWER: No head-to-head studies directly compare all the main treatments for venous thromboembolism (VTE) in cancer patients. Long-t...
Article
- Author:
- Gary Kelsberg, MD
Publish date: August 1, 2018
EVIDENCE-BASED ANSWER: Treating patients with Helicobacter pylori infection who have failed clarithromycin-based triple therapy with either ...
