ArticleEffective and Safe Combination Therapy for Severe Acne Vulgaris: A Randomized, Vehicle-Controlled, Double-blind Study of Adapalene 0.1%–Benzoyl Peroxide 2.5% Fixed-Dose Combination Gel With Doxycycline Hyclate 100 mgAuthor:Cruz APublish date: February 1, 2010 There is a paucity of treatment options for severe acne vulgaris aside from oral isotretinoin. Read More