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Active psoriatic arthritis, ankylosing spondylitis linked to increase in adverse pregnancy outcomes
Women with psoriatic arthritis and ankylosing spondylitis generally have favorable pregnancy outcomes, but high disease activity during pregnancy...
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Antiangiogenics linked to fatal bleeds after RT in patients with “ultracentral” lung tumors
Of six fatal pulmonary hemorrhages, four occurred in patients receiving bevacizumab or pazopanib within 30 days of stereotactic body radiation...
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Skip metastasis rate low in node-negative oral cancers
Supraomohyoid neck dissection is likely adequate for the subset of patients with oral cancer and node-negative disease.
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Smoking rates remain steady among the poor
Public policies that consider socioeconomic and health-related disparities in isolation may miss the big picture.
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Do some EGFR mutation subtypes benefit from immune checkpoint blockade?
One common EGFR tyrosine kinase inhibitor–sensitizing allele may be associated with similar benefit versus EGFR wild-type lung tumors, analysis...
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More than 40% of U.K. physicians report binge drinking
“We recommend that doctors’ mentors, supervisors, peers, and occupational health support services recognize and act on the prevalence of...
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Evobrutinib demonstrates efficacy, safety in relapsing MS
PHILADELPHIA – Primary endpoint of reducing enhancing lesions versus placebo was met with evobrutinib.
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Fingolimod reduced disease activity more than glatiramer acetate in RRMS: ASSESS study results
PHILADELPHIA – Relapse rate and radiographic endpoints significantly improved with the 0.5-mg daily dose of fingolimod, with safety as expected...
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Ocrelizumab effective, safe in relapsing-remitting MS patients
PHILADELPHIA - A positive risk-to-benefit ratio over nearly 1 year for the anti-CD20 monoclonal antibody.
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Deutetrabenazine benefit may increase over time in patients with tardive dyskinesia
PHILADELPHIA – Interim results of an open-label study suggest that changes in AIMS score are at least maintained over the course of nearly 3 years...
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Biomarker-based score predicts poor outcomes after acute ischemic stroke
PHILADELPHIA – A free app and online calculator are available to calculate the four-item ‘CoRisk’ score.
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Perplexing text messages may be the sole sign of stroke
PHILADELPHIA – The diagnostic importance of “dystextia” is more important now than ever given the ubiquity of smartphones.
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Rotavirus vaccine had strong protective effect in routine U.K. practice
Vaccine effectiveness was high in children with laboratory-confirmed rotavirus infection, although effects on all-cause gastroenteritis could not...
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Eculizumab cuts relapse risk in NMO spectrum disorder
PHILADELPHIA – Nearly 98% of patients with this autoimmune inflammatory CNS disorder were relapse-free at 48 weeks in the randomized phase 3...
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Fournier gangrene cases surge in patients using SGLT2 inhibitors
Serious complications and death are likely if Fournier gangrene is not recognized.