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Phase 2 studies show potential of FcRn blockade in primary ITP
ORLANDO – The results support continued investigation in phase 3 trial for rozanolixizumab and efgartigimod, according to investigators.
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New ASH guideline: VTE prophylaxis after major surgery
ORLANDO – The chair of VTE guidelines panel presented highlights of the latest guidelines in a special session at the annual meeting of the...
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Fibrosis scoring systems have ‘modest’ predictive value in general population
For predicting severe liver disease, investigators say today’s scoring systems lack precision in unselected populations with low prevalence of...
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Efficacy of postvenetoclax therapy may depend on prior agent exposure in CLL
ORLANDO – The multicenter study was aimed at addressing the knowledge gap around what therapy to use after venetoclax.
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Fragmentation of sickle cell disease care starts in young adulthood
ORLANDO – Imagine what that would be like to have a chronic, debilitating illness and to have to go to multiple different hospitals, during this...
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Kidney function in African American AML patients not linked to reduced survival compared with whites
ORLANDO –
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Bispecific CAR T-cells yield high response rate in relapsed/refractory myeloma
ORLANDO – Duration of response, manageable safety support further investigation of dual-targeted strategy, according to investigator.
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In UC patients, tofacitinib tied to modest, reversible lipid increases, infrequent cardiovascular events
The observation period was still relatively short, however so longer-term data may be needed to more fully characterize lipid impact and...
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No clear-cut evidence of vedolizumab effect in retrospective study of primary sclerosing cholangitis
Cholestasis markers dropped in some, but not all, patients with primary sclerosing cholangitis and inflammatory bowel disease, though a...
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Early colonoscopy for acute lower GI bleeding fails to improve diagnostic yield or reduce rebleeding rate
Compared with elective colonoscopy, recommended procedure resulted in no statistical difference in primary or key secondary outcome.
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What’s new in hepatitis C: Four themes that dominated at the Liver Meeting
BOSTON – AASLD highlights included treatment of persons who inject drugs, new directions in pangenotypic therapy,...
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Skin barrier dysfunction mutations vary by race, disease persistence in children with AD
Findings may have implications for genetic test development, investigators note.
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AASLD debrief: Five drugs show promise in NAFLD (and two do not)
BOSTON – Promising new data for cotadutide, licogliflozin, tropifexor, saroglitazar, and PF-05221304 highlighted in...
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TARGET-NASH: One-third of NAFLD, NASH patients lost weight, but not all kept it off
BOSTON – With no approved pharmacologic treatments for NAFLD and NASH, weight reduction remains one of the mainstays of treatment.
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Ask about vaping in patients with respiratory symptoms, CDC says
New CDC recommendations intended to help HCPs pinpoint and manage vaping-associated lung injuries as seasonal respiratory infections trend upward...