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ZUMA-12 study shows frontline axi-cel has substantial activity in high-risk large B-cell lymphoma
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Allogeneic transplant leads to durable remissions in T-cell lymphomas
Retrospective study demonstrates overall survival over 50% at 5 years, though transplant-related mortality and graft-versus-host disease need to...
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ZUMA-5: Axi-cel yields high response rate in indolent NHL
The CAR T-cell therapy had a favorable safety profile and a median duration of response that had not been reached at a median of 17.5 months...
Article
ASCO advises against PARP inhibitor retreatment in ovarian cancer
ASCO guidelines detail recommendations for PARP inhibitor treatment in ovarian cancer.
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OSA diagnoses not carried forward to the inpatient setting
Missed OSA diagnoses could have especially negative implications for patients who don’t continue on positive airway pressure (PAP) therapy during...
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Switching to riociguat effective for some patients with PAH not at treatment goal
The clinical benefit of the switching to the sGC inhibitor was consistent across patient subgroups in the phase 4 REPLACE study.
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Certain statins linked to lower mortality risk in patients admitted for sepsis
Statin use was associated with lower mortality, compared with no use, with hydrophilic and synthetic statins besting lipophilic and fungal-derived...
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COVID-19 experience forced residents to quickly improve patient communication skills
At the peak of the pandemic in New York City, goals of care discussions became easier, though coping with death remains an issue.
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National lung cancer screening guidelines may miss younger African American individuals at high risk
Retrospective analysis finds many lung cancer patients would not have counted as eligible for low-dose CT under guidelines that are being...
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Fauci: Cautious optimism for COVID-19 vaccine by end of 2020
Top health official is “cautiously optimistic” for vaccine distribution before end of year, pending favorable safety and efficacy data.
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COVID-19 outcomes no worse in patients on TNF inhibitors or methotrexate
No increase was seen in hospitalization and death rates, providing additional support for keeping patients on these immunosuppressive treatments...
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ctDNA clearance tracks with PFS in NSCLC subtype
The median progression-free survival was significantly longer for patients with circulating tumor DNA clearance.