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BMI compares favorably with body scanning for ID of cardiometabolic traits
BMI may be all that’s needed to identify metabolic risk factors in young persons.
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‘Optimal’ pazopanib levels linked to lower toxicity in RCC patients
Therapeutic drug monitoring may help optimize dosing and limit toxicity, though larger studies are needed to validate this small, retrospective...
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Cytoreductive nephrectomy may benefit RCC patients with brain mets
In an analysis of SEER data, 2-year survival was 52% and 14%, respectively, for RCC patients with brain-only metastases who did and did not...
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Lipoprotein ratio linked to poor survival in metastatic RCC
In a retrospective study of data on 287 metastatic RCC patients who underwent cytoreductive nephrectomy, the ratio of apolipoproteins B and A1 was...
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RCC strongly linked to melanoma, and vice versa
Clinicians need to be vigilant for RCCs in melanoma patients, and for melanomas in RCC patients.
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Emapalumab found safe, effective in primary HLH
SAN DIEGO—Emapalumab, an interferon gamma-blocking antibody, controls disease activity and has a favorable safety profile in pediatric patients...
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Rapid test could solve Africa’s sickle cell screening problem
SAN DIEGO – The simple blood test costs about $2 and has an accuracy of 99%.
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Rivaroxaban may reduce VTE risk in cancer patients
SAN DIEGO – The CASSINI trial evaluates VTE prophylaxis in ambulatory patients receiving systemic therapy.
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HU could save millions of lives in Africa, speaker says
SAN DIEGO—Daily hydroxyurea (HU) treatment is feasible, safe, and effective for children with sickle cell disease (SCD) in sub-Saharan Africa,...
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DOAC pause yields favorable outcomes for AF patients
SAN DIEGO – Results from the PAUSE study could set the standard for timing of perioperative DOAC interruption.
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Early intervention initiative cut oncology patient hospitalizations
An after-hours phone triage system, proactive chemotherapy follow-up calls, and a Saturday-Sunday urgent care clinic resulted in early...
Video
Sickle cell disease guidelines release set for early 2019
SAN DIEGO – Five new ASH guidelines for sickle cell disease are on the way, likely early in 2019.
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Emapalumab safe, effective in pediatric primary hemophagocytic lymphohistiocytosis
SAN DIEGO – There is “certainly room for enlarging the indication” to first-line treatment of HLH once a sufficient number of previously untreated...
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Ixazomib improves PFS after ASCT in MM
SAN DIEGO—Ixazomib improved progression-free survival (PFS) following autologous stem cell transplant (ASCT) in patients with newly diagnosed...
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Lower-dose rituximab may be enough in acquired TTP
SAN DIEGO – A lower dose of rituximab appears effective, but it still carries side effects.