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COPD exacerbations associated with poor sleep quality
After 18 months of follow-up, patients with at least one exacerbation of COPD had a median baseline Pittsburgh Sleep Quality Index score of 6.0,...
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Cognitive decline sped up after CHD
The acceleration in cognitive decline persisted for years after incident CHD.
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Tofacitinib upped herpes zoster risk in ulcerative colitis
Over a median of 1.4 years, therapy was otherwise safe, compared with placebo.
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Inducible nitric oxide synthase promotes insulin resistance in obesity
The findings could lead to new treatments for metabolic diseases.
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Acetyl-coenzyme-A carboxylase inhibition shows early promise for acne vulgaris
Two weeks of treatment approximately halved facial sebum production.
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Systematic review indicates cutaneous laser therapy may be safe during pregnancy
Elective laser treatments are usually not recommended during pregnancy, but no evidence supports this, according to the authors of the review.
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Tofacitinib upped herpes zoster risk in ulcerative colitis
Over a median of 1.4 years, therapy was otherwise safe, compared with placebo.
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Crohn’s: Red meat avoidance won’t prevent flares
There were no significant differences in time to any symptomatic relapse between the high– and low–red meat diet groups at the end of the study....
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Revision total joint replacements linked to higher infection risk
The 90-day risk of surgical site infection was 5.77 times higher after revision vs. primary total joint replacement.
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TEG-guided topped conventional transfusion in cirrhotic patients with variceal bleeding
With TEG, only four (13.3%) patients received transfusions, compared with every patient in the conventional transfusion group (P less...
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Zoster vaccination is underused but looks effective in IBD
For men with inflammatory bowel disease, herpes zoster vaccination was associated with about a 46% decrease in risk of associated infection...
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BMI in male teens predicts cardiomyopathy risk
The hazard ratio for dilated cardiomyopathy in adulthood was 1.38 when adolescent body mass index was 22.5-25.0 kg/m2 – and rose to 8....
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Pancreatic cancers often contained targetable mutations
A total of 17% of specimens harbored mutations that are potentially targetable with existing therapies. These mutations involved either RTK/ras/...
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Infections within first year of life predicted IBD
The correlation was strongest for onset by age 10 years.
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Induction trough levels predicted ustekinumab response in Crohn’s disease
An ustekinumab trough level of 2.0 mcg/mL or higher distinguished responders from nonresponders with an area under the receiver operating curve of...