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Trial of epicutaneous immunotherapy in eosinophilic esophagitis
The per-protocol analysis suggested that there was a lower eosinophil count with active treatment. .
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Eradicating H. pylori may cut risk of gastric cancer
Treatment without eradication was associated with an increase in risk.
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Long-term entecavir looks safe, effective in HBV
The entecavir and nonentecavir trial arms did not significantly differ in time-to-event analyses of malignant neoplasms, liver-related HBV disease...
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Gastric electrical stimulation device may improve refractory vomiting
However, gastric electrical stimulation did not significantly improve the coprimary endpoint of quality of life.
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Postcolonoscopy colorectal cancers had unique features
Their predisposition to the proximal colon and to microsatellite instability suggests that they have unique characteristics of tumorigenesis.
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Level of hepatitis B core–related antigen is risk factor for hepatocellular carcinoma
Compared with patients whose HBcrAg level was less than 10 KU/mL, a level of 10-99 KU/mL was associated with a nearly threefold increase in risk...
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Daily aspirin might cut risk of fibrosis progression
The researchers did not find a similar protective effect for NSAIDs other than aspirin.
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Threshold for positivity affects FIT sensitivity for detecting CRC, advanced adenomas
Specificity varied together with positivity thresholds, but less substantially than sensitivity.
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AGA Clinical Practice Update: Coagulation in cirrhosis
Consider alternatives to blood products to mitigate the risk of worsening portal hypertension, infection, and immunologic complications.
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Atypical food allergies common in IBS
Many patients with irritable bowel syndrome have atypical food allergies and improve with appropriate elimination diets.
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Endoscopist personality linked to adenoma detection rate
Endoscopists’ self-reported personality traits correlated significantly with their rates of adenoma detection.
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COPD exacerbations associated with poor sleep quality
After 18 months of follow-up, patients with at least one exacerbation of COPD had a median baseline Pittsburgh Sleep Quality Index score of 6.0,...
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Cognitive decline sped up after CHD
The acceleration in cognitive decline persisted for years after incident CHD.
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Tofacitinib upped herpes zoster risk in ulcerative colitis
Over a median of 1.4 years, therapy was otherwise safe, compared with placebo.
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Inducible nitric oxide synthase promotes insulin resistance in obesity
The findings could lead to new treatments for metabolic diseases.