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Commentary: Composite risk, not age, is key for timing first colorectal cancer screening
Age may not be the colorectal cancer screening issue.
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AGA Guideline: Treatment of opioid-induced constipation
Laxative therapies, including stimulant laxatives are recommended; for truly laxative-refractory constipation, a trial of peripherally acting mu-...
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Pancreatic surveillance identified resectable cancers
Nine of ten tumors were resectable and 85% of these patients survived at least 3 years.
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Study examines POEM learning curve
The typical learning curve was 100 cases.
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Even modest alcohol use may worsen NAFLD
Modest alcohol consumption was associated with significantly less improvement in steatosis and significantly lower odds of NASH resolution.
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Avatrombopag cut procedure-related transfusions in patients with thrombocytopenia, chronic liver disease
In both trials, the primary endpoint met a high degree of statistical significance.
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Proinflammatory diet linked to colorectal cancer testing positive for Fusobacterium nucleatum
Dietary scores in the highest tertile correlated with significantly increased risk (P = .03).
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Cirrhosis study finds no link between screening, liver cancer mortality
Among patients with cirrhosis, screening for hepatocellular carcinoma was not associated with reductions in liver cancer mortality.
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Experts update diagnostic guidelines for eosinophilic esophagitis
The diagnosis no longer needs to include a trial of proton pump inhibitor therapy.
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AGA Clinical Practice Update: Tumor seeding with endoscopic procedures
Some endoscopic procedures may seed the tumors that were performed to diagnose.
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Study models surveillance interval after ablation of Barrett’s esophagus
Baseline histologic grade was the most important predictor of recurrence.
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Endoscopic screening tied to significantly lower risk of death from gastric cancer
Compared with no screening, the reduction in risk was 40%.
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Treatment simulation could help personalize myeloma therapy
A simulation helped identify whether patients would benefit most from treatment with bortezomib or lenalidomide.
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Fine-needle aspirate, biopsy found equivalent in randomized trial
Diagnostic yields were 91% for fine-needle aspirate and 89% for fine-needle biopsy.
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Who are the 'high-need, high-cost' patients?
Significant predictors included Medicare or Medicaid insurance, lower income, first hospitalization in a large rural hospital, high comorbidity...