ArticleThrombotic thrombocytopenic purpura: The role of ADAMTS13Author:Alan E. Lichtin, MDPublish date: August 1, 2016ADAMTS13 testing is useful in diagnosing this disease, guiding therapy, and predicting relapse.Read More
ArticleAnkle pain in a young woman with Gaucher diseaseAuthor:Alan E. Lichtin, MDPublish date: September 1, 2015Gaucher disease causes hepatomegaly, splenomegaly, bone marrow disease, bone pain, bone infarcts, and lytic lesions.Read More
ArticleA 54-year-old woman with pancytopeniaAuthor:Alan E. Lichtin, MDPublish date: December 1, 2011Her red blood cell, white blood cell, and platelet counts are all low. What is the cause?Read More
ArticleHow safe are erythropoiesis-stimulating agents?Author:Alan E. Lichtin, MDPublish date: May 1, 2008The year 2007 was a rough one for these agents, and the story is far from over.Read More
ArticleAcute leukemia with a very high leukocyte count: Confronting a medical emergencyAuthor:Alan E. Lichtin, MDPublish date: August 1, 2004From 5% to 30% of adult patients with acute leukemias present with hyperleukocytosis and leukostasis. Prompt action is needed.Read More
ArticleClopidogrel and thrombotic thrombocytopenic purpura: No clear case for causalityAuthor:Alan E. Lichtin, MDPublish date: May 1, 2003Current evidence neither establishes nor refutes a causal relationship between the drug and this potentially fatal disorder.Read More
ArticleWhat is the best way to determine if thrombocytopenia in a patient on multiple medications is drug-induced?Author:Alan E. Lichtin, MDPublish date: March 1, 2002The only way is to stop the suspected drug and see if the thrombocytopenia resolves. But how to avoid stopping needed drugs that are not a problem?...Read More
ArticleWhat evaluation should be done for an apparently healthy patient with an increased mean corpuscular volume (MCV)?Author:Alan E. Lichtin, MDPublish date: May 1, 2001Seemingly trivial symptoms, easily overlooked, can lead to the correct diagnosis.Read More
