Conference Coverage

Prehospital antibiotics improved some aspects of sepsis care

 

Key clinical point: In patients with suspected sepsis, prehospital antibiotics delivered by EMS personnel improved some aspects of care, but did not reduce mortality.

Major finding: At 28 days, 120 patients (8%) in the prehospital antibiotics group had died, compared with 93 patients (8%) in the usual care group (relative risk, 0.95; 95% CI, 0.74-1.24).

Data source: Intention-to-treat analysis of 2,672 patients in a prospective randomized, controlled open-label trial comparing early prehospital antibiotics to standard care.

Disclosures: The study authors declared no competing interests related to the study.

Source: Alam N et al. Lancet Respir Med. 2018 Jan;6(1):40-50.


 

REPORTING FROM CCC47

Training EMS personnel in early recognition of sepsis improved some aspects of care within the acute care chain, but did not reduce mortality, according to results of a randomized trial.

Emergency medical service (EMS) personnel were able to recognize sepsis more quickly, obtain blood cultures, and give antibiotics after the training, reported investigator Prabath Nanayakkara, MD, PhD, FRCP, at the Society of Critical Care Medicine’s Critical Care Congress.

Dr. Prabath Nanayakkara of the department of internal medicine at VU University Medical Center, Amsterdam Andrew Bowser/Frontline Medical News

Dr. Prabath Nanayakkara

However, the hypothesis that this training would lead to increased survival was not met, noted Dr. Nanayakkara, of the acute medicine section of the department of internal medicine at VU University Medical Center, Amsterdam.

At 28 days, 120 patients (8%) in the prehospital antibiotics group had died, compared with 93 patients (8%) in the usual care group (relative risk, 0.95; 95% confidence interval, 0.74-1.24), according to the study’s results that were simultaneously published online in Lancet Respiratory Medicine.

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