Case-Based Review

Cases That Test Your Skills

The teenager who couldn’t stay awake

Mr. G, age 14, presents to the ED with hypersomnolence and altered mental status. Drug screens are negative. What could be causing these symptoms...

Savvy Psychopharmacology

Making sense of CYP2D6 and CYP1A2 genotype vs phenotype

The clinical response to the same dose of a drug may vary among individuals. Cytochrome P450 (CYP) 2D6 and 1A2 are enzymes that metabolize many...

Savvy Psychopharmacology

Treating psychosis in patients with HIV/AIDS

Mr. S, age 56, has human immunodeficiency virus (HIV) and schizoaffective disorder.

Cases That Test Your Skills

A 95-year-old man with treatment-resistant depression

Mr. R, age 95, presents with depressive symptoms that began 6 weeks ago. He recently has lost 20 lb and is rapidly deteriorating. Which treatment...