Key clinical point: IV dexamethasone was significantly associated with pain relief in knee surgery patients at 12, 15, 18, and 21 hours post-surgery.
Major finding: Patients given IV dexamethasone averaged 11 points lower VAS scores for pain at rest and 15 points lower for pain in motion compared with placebo patients.
Study details: The data come from a randomized trial of 100 patients who underwent total knee arthroplasty.
Disclosures: The researchers had no relevant financial conflicts
Tammachote N et al. J Arthroplasty. 2019. doi: https://doi.org/10.1016/ j.arth.2019.09.002