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Severe fibrosis persists after bariatric surgery in almost half of NASH patients

Key clinical point: For almost half of patients with nonalcoholic steatohepatitis, bariatric surgery does not resolve severe fibrosis.

Major finding: At follow-up liver biopsy, 45% of patients had persistent severe fibrosis despite losing an average of one-quarter of their baseline bodyweight.

Study details: A retrospective and observational study involving 868 patients with nonalcoholic steatohepatitis who underwent bariatric surgery.

Disclosures: The investigators disclosed relationships with Allergan, Boehringer Ingelheim, Novo Nordisk, and others.


Pais R et al. The Liver Meeting 2019, Abstract 66.