Journal Club
Journal Club
Sorafenib extends PFS for refractory desmoid tumors
The oral tyrosine kinase inhibitor was associated with durable responses and a high progression-free survival rate in patients with refractory or...
News
TKIs and immunotherapy hold promise for alveolar soft part sarcoma
Tyrosine kinase inhibitors and immune checkpoint inhibitors show encouraging results in the treatment of alveolar soft part sarcoma
News
PARP inhibitor plus trabectedin shows promise for sarcoma
Investigators planning phase 2 studies after phase 1b results demonstrated tolerability and efficacy with the combination of olaparib and...
Journal Club
Novel molecular assay: Promising results in bone and soft tissue tumor evaluation
Two new fusion partners for the USP6 gene were found using AMP-based targeted next-generation sequencing.
News
Chromoplexy linked to aggressive Ewing sarcomas
Analysis of the sequence context surrounding chromoplexy breaks may provide clues and potentially point to a therapeutic vulnerability that could...
Journal Club
Sarcoma dominance in uterine carcinosarcomas linked to decreased survival
News
Targetable genetic alterations found in 41% of soft tissue sarcomas
Next-generation sequencing results might prove useful for guiding targeted therapy that could improve the treatment outcomes of patients with...