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PROMIS Forms Capture Fatigue Experience in RA

Qual Life Res; ePub 2018 May 24; Bartlett, et al

Items in the single-score PROMIS Fatigue Short Forms (SFs) demonstrate content validity and can adequately capture the wide range of fatigue experiences of people with rheumatoid arthritis (RA), a recent study found. Researchers recruited people with RA from an online patient community (n=200) and 3 academic medical centers (n=84) in the US. Participants completed both SFs then rated the comprehensiveness and comprehensibility of the items to their fatigue experience. Researchers found:

  • Mean SF scores were similar among clinic patients reflecting mild fatigue (ie, 54.5–55.9), but were significantly higher in online participants.
  • SF Fatigue scores correlated highly (r ≥ 0.82) and moderately with patient assessments of disease activity (r ≥ 0.62).
  • Most (70–92%) reported that the items “completely” or “mostly” reflected their experience.
  • Almost all (≥ 94%) could distinguish general fatigue from RA fatigue.
  • Most (≥ 85%) rated individual items questions as “somewhat” or “very relevant” to their fatigue experience, averaged their fatigue over the past 7 days (58%), and rated fatigue impact vs severity (72 vs 19%).
  • 99% rated fatigue as an important symptom they considered when deciding how well their current treatment was controlling their RA.

Citation:

Bartlett SJ, Gutierrez AK, Butanis A, et al. Combining online and in-person methods to evaluate the content validity of PROMIS fatigue short forms in rheumatoid arthritis. [Published online ahead of print May 24, 2018]. Qual Life Res. doi:10.1007/s11136-018-1880-x.

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