Key clinical point: Gene expression and DNA methylation patterns show association with treatment response in rheumatoid arthritis.
Major finding: A machine learning model based on gene expression and epigenetic features shows accuracy in predicting RA treatment response.
Study details: An observational cohort study involving 80 patients with rheumatoid arthritis.
Disclosures: The study was supported by AbbVie, and two authors were supported by the China Scholarship Council and the Netherlands Organisation for Scientific Research. No conflicts of interest were declared.
Tao W et al. Arthritis Rheumatol. 2020 Sep 10. doi: 10.1002/art.41516.