Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Psoriasis with Arthritis Linked with Hearing Impairment

J Rheumatol; ePub 2019 Jan 15; Semenov, et al

Psoriasis with arthritis (PsA) is independently associated with a significantly increased risk of hearing impairment (HI), which partially mediates an association with worsened psychiatric outcomes, according to a recent study. Researchers conducted a cross-sectional study using the National Health and Nutrition Examination Survey (NHANES) for adults aged ≥20 years (n=10,747). The association of PsA with the aforementioned outcomes was examined using multivariable generalized linear and ordinal logistic regression models, adjusted for demographics and medical comorbidities. Structural equation models examined the extent to which HI mediated the effect of PsA on mental health. They found:

  • Individuals with PsA were more likely to report hearing difficulties (odds ratio [OR] 1.50), visit a mental health provider (OR 1.62), have 1.62 more days of poor mental health over the previous month, and have depression (OR 2.01) compared to controls.
  • HI mediated 6.5%, 8.3%, and 5.0% of the effect of PsA on the above mental health outcomes, respectively.

Citation:

Semenov YR, Hsiang EY, Huang A, et al. Association between psoriasis with arthritis and hearing impairment in US adults: Data from the National Health and Nutrition Examination Survey. [Published online ahead of print January 15, 2019]. J Rheumatol. doi:10.3899/jrheum.171228.

This Week's Must Reads

Long-term Opioid Use with Severe OA by Geography, Arthritis Rheumatol; ePub 2019 Jan 28; Desai, et al

Family History of Psoriasis and Psoriatic Disease, Arthritis Care Res; ePub 2019 Jan 25; Solmaz, et al

Remission/Low Disease Activity Protective in SLE , Lupus; ePub 2019 Jan 24; Alarcón, Ugarte-Gil, et al

Dietary Niacin Linked with Incident Hip Fracture, J Bone Miner Res; ePub 2019 Jan 19; Carbone, et al

Must Reads in Psoriatic arthritis

Family History of Psoriasis and Psoriatic Disease, Arthritis Care Res; ePub 2019 Jan 25; Solmaz, et al

Psoriasis with Arthritis Linked with Hearing Impairment, J Rheumatol; ePub 2019 Jan 15; Semenov, et al

Assessing Back Pain Criteria in Psoriatic Arthritis, Ann Rheum Dis; 2018 Nov; Yap, Ye, et al

FDA Approves Hyrimoz for Chronic Conditions, Sandoz news release; 2018 Oct 31

T2D Risk in PsA Higher than in General Population , Rheumatology (Oxford); ePub 2018 Sep 6; Charlton, et al