Psoriasis with arthritis (PsA) is independently associated with a significantly increased risk of hearing impairment (HI), which partially mediates an association with worsened psychiatric outcomes, according to a recent study. Researchers conducted a cross-sectional study using the National Health and Nutrition Examination Survey (NHANES) for adults aged ≥20 years (n=10,747). The association of PsA with the aforementioned outcomes was examined using multivariable generalized linear and ordinal logistic regression models, adjusted for demographics and medical comorbidities. Structural equation models examined the extent to which HI mediated the effect of PsA on mental health. They found:
- Individuals with PsA were more likely to report hearing difficulties (odds ratio [OR] 1.50), visit a mental health provider (OR 1.62), have 1.62 more days of poor mental health over the previous month, and have depression (OR 2.01) compared to controls.
- HI mediated 6.5%, 8.3%, and 5.0% of the effect of PsA on the above mental health outcomes, respectively.
Semenov YR, Hsiang EY, Huang A, et al. Association between psoriasis with arthritis and hearing impairment in US adults: Data from the National Health and Nutrition Examination Survey. [Published online ahead of print January 15, 2019]. J Rheumatol. doi:10.3899/jrheum.171228.