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Step Rate and Worsening of PF and TF Osteoarthritis

Arthritis Care Res; ePub 2019 Mar 1; Hart, et al

Lower step rate was associated with increased risk of cartilage damage worsening in the lateral patellofemoral joint (PF) and tibiofemoral joint (TF) compartments in women and worsening medial TF damage in men, a recent study found. Researchers utilized data from The Multicenter Osteoarthritis Study (MOST), a prospective cohort of men and women with or at risk of knee osteoarthritis. Self‐selected step rate was measured using an instrumented GAITRite walkway at the 60‐month visit. Cartilage damage was semi‐quantitatively graded on magnetic resonance images at the 60- and 84‐month visits in the medial and lateral PF and TF compartments. They found:

  • 1,089 participants (age, 66.9±7.5 years; body mass index, 29.6±4.7kg/m2; women, 62.3%) were included.
  • Women with the lowest step rate had increased risk of lateral PF (risk ratio: 2.1) and TF (1.8) cartilage damage worsening 2 years later compared to those with the highest step rate.
  • Men with the lowest step rate had increased risk of medial TF cartilage damage worsening 2 years later (2.1).

Hart HF, Gross KD, Crossley KM, et al. Is step rate associated with worsening of patellofemoral and tibiofemoral joint osteoarthritis in women and men? The Multicenter Osteoarthritis Study. [Published online ahead of print March 1, 2019]. Arthritis Care Res. doi:10.1002/acr.23864.