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Imaging Reveals Different Clinico-Pathologic Patterns in Takayasu’s, Giant Cell Arteritis

Key clinical point: The associations between findings on MR angiography (MRA) and 18F-fluorodeoxyglucose (FDG) PET and differing clinical symptom presentations in patients with Takayasu’s arteritis and those with giant cell arteritis may be used to predict imaging pathology.

Major finding: Arm claudication was the most commonly reported symptom overall, present in 52% of those with Takayasu’s arteritis and 28% of those with giant cell arteritis. It was more strongly associated with subclavian artery damage on MRA than with inflammation on FDG-PET.

Study details: The cohort comprised 56 patients with Takayasu’s arteritis and 54 with giant cell arteritis who together had made 270 visits.

Disclosures: The Division of Intramural Research at the National Institute of Arthritis and Musculoskeletal and Skin Diseases funded the research. The investigators had no financial disclosures.

Citation:

Michailidou D et al. Ann Rheum Dis. 2019 Oct 24. doi: 10.1136/annrheumdis-2019-216145.