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Hospitalization Increases Risk of Gout Flares

J Rheumatol; ePub 2018 Jul 1; Zleik, et al

Hospitalization increased the risk of gout flares 10-fold, according to a recent study, and in-hospital gout flares were associated with longer hospitalization. Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989–1992 or 2009–2010. 429 patients were followed up to 5 years. Researchers found:

  • Of total patients, 169 patients experienced 454 hospitalizations.
  • Hospitalization rates increased without reaching statistical significance from 1989–1992 to 2009–2010 (rate ratio [RR] 1.190).
  • The gout flare rate increased significantly during hospitalization (RR 10.2).
  • In-hospital gout flare increased the average hospital stay by 1.8 days.


Zleik N, Elfishawi MM, Kvrgic, et al. Hospitalization increases the risk of acute arthritic flares in gout: A population-based study over 2 decades. [Published online ahead of print July 1, 2018]. J Rheumatol. doi:10.3899/jrheum.171320.