Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Juvenile Dermatomyositis Derails Growth and Pubertal Development

Key clinical point: Children in early puberty during the active phase of juvenile dermatomyositis had the highest risk of growth failure.

Major finding: Growth failure occurred in 21% of girls and 15% of boys with juvenile dermatomyositis over the course of a 2-year study.

Study details: The data come from a longitudinal cohort study of 196 children with juvenile dermatomyositis.

Disclosures: The study was supported by the European Union, Helse Nord Research grants, and by IRCCS Istituto Giannina Gaslini. Five authors of the study reported financial relationships with pharmaceutical companies.


Nordal E et al. Arthritis Care Res. 2019 Sep 10. doi: 10.1002/acr.24065.