Clinical Edge

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New lupus classification criteria perform well in children, young adults

Key clinical point: The American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR) 2019 systemic lupus erythematosus (SLE) classification criteria has superior sensitivity for classifying the disease in children and young adults in comparison with the 1997 ACR criteria, but similar specificity for the condition.

Major finding: The 2019 criteria had significantly higher sensitivity than did the 1997 criteria (85% vs. 72%, respectively; P = .023) but similar specificity (83% vs. 87%; P = .456).

Study details: A review of electronic medical records of 112 SLE patients aged 2-21 years and 105 controls aged 1-19 years at the Cincinnati Children’s Hospital Medical Center during 2008-2019.

Disclosures: There was no funding secured for the study, and the authors had no conflicts of interest to disclose.


Aljaberi N et al. Arthritis Care Res. 2020 Aug 25. doi: 10.1002/acr.24430.