Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Inflammatory Arthritis a Risk for THA Complications

J Arthroplasty; ePub 2019 Feb 18; Richardson, et al

Patients with inflammatory arthritis (IA) have significantly higher risk of transfusion, mechanical complications, infection, and readmission following total hip arthroplasty (THA), according to a recent study. Therefore, efforts should be made to optimize their health and medications before THA to minimize their complication risk. Additionally, hospitals should receive commensurate resources to maintain access to THA for patients with IA who are prone to higher resource utilization. A national private insurance database was used to select patients undergoing unilateral primary THA. Patients were categorized to the inflammatory cohort if they had a diagnosis of IA and treatment with an IA-specific medication within the year before surgery. Researchers found:

  • A total of 68,348 patients were included; 2.12% met criteria for IA.
  • Patients with IA were found to have higher risk of transfusion (odds ratio [OR], 1.29), mechanical complications (OR, 1.35), infection (OR, 1.96), and 90-day readmission (OR, 1.35).
  • There were no differences in risk of venous thromboembolism or medical complications.


Richardson SS, Kahlenberg CA, Goodman SM, et al. Inflammatory arthritis is a risk factor for multiple complications after total hip arthroplasty: A population-based comparative study of 68,348 patients. [Published online ahead of print February 18, 2019]. J Arthroplasty. doi:10.1016/j.arth.2019.02.018.

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