Clinical Edge

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Continuous NSAID use for ankylosing spondylitis may raise hypertension risk

Key clinical point: Continuous NSAID use could increase the risk of incident hypertension among patients with ankylosing spondylitis.

Major finding: NSAID use was associated with a 12% increased risk of incident hypertension.

Study details: A prospective cohort study involving 1,282 patients with ankylosing spondylitis.

Disclosures: The investigators reported funding from the National Institutes of Health, the Assessment of Spondyloarthritis International Society, the Spondylitis Association of America, and the Russel Engleman Rheumatology Research Center at the University of California, San Francisco. Some authors reported ties with Eli Lilly, Novartis, and other pharmaceutical companies.


Liew et al. Arthritis Care Res. 2019 Sep 17. doi: 10.1002/acr.24070.