Clinical Edge

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Ankylosing Spondylitis Severity, Comorbidities Higher in Blacks Than in Whites

Key clinical point: Although ankylosing spondylitis (AS) is more common among whites, blacks appear to express higher disease activity.

Major finding: More blacks with AS (vs. whites) had elevated erythrocyte sedimentation rate (62% vs. 48%), C-reactive protein (68% vs. 54%) and significantly higher rates of anterior uveitis (8% vs. 4%), hypertension (29% vs. 22%), diabetes (27% vs. 17%), and depression (36% vs. 32%).

Study details: The retrospective database review comprised 10,990 patients with AS.

Disclosures: The authors reported no potential conflicts of interest and no source of financial support.


Singh DK et al. J Rheumatol. 2019 Sep 1. doi: 10.3899/jrheum.181019.