Portopulmonary Hypertension
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Saira Aijaz Khaderi, MD
Abdominal Transplant & Liver Disease Center, Baylor College of Medicine, Houston, TX

Zeenat Safdar, MD, MS

Pulmonary-Critical Care Medicine, Houston Methodist Lung Center, Houston, TX

Question 1 of 5

Questions 1–5 are based on the following case:

A 56-year-old Caucasian man with cirrhosis secondary to hepatitis C who is listed for liver transplant presents to your office for dyspnea with exertion. On exam he has spider angiomas, palmar erythema, and an accentuated pulmonary component of the second heart sound. Oxygen saturation is 95% on room air. Echocardiogram shows a right ventricular systolic pressure of 50 mm Hg and normal right and left ventricular function. You decide to evaluate the patient for portopulmonary hypertension (POPH) and perform a right heart catheterization.

Which of the following data on right heart catheterization are diagnostic for POPH?

Mean pulmonary artery pressure (MPAP) 20 mm Hg, pulmonary vascular resistance (PVR) 200 dynes/s/cm–5, pulmonary capillary wedge pressure (PCWP) 5 mm Hg, cardiac output 5 L/min

MPAP 30 mm Hg, PVR 200 dynes/s/cm–5, PCWP 10 mm Hg, cardiac output 6.5 L/min

MPAP 30 mm Hg, PVR 240 dynes/s/cm–5, PCWP 25 mm Hg, cardiac output 5 L/min

MPAP 35 mm Hg, PVR 320 dynes/s/cm–5, PCWP 10 mm Hg, cardiac output 5 L/min

This quiz is not accredited for CME.

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