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Combined PH subtypes predicts poor survival in kidney disease

Key clinical point: Pulmonary hypertension is common and certain subtypes are associated with poor survival in chronic kidney disease patients.

Major finding: Among adults with chronic kidney disease, combined pre- and postcapillary pulmonary hypertension was associated with higher mortality risk, compared with no pulmonary hypertension (hazard ratios of 1.89, 1.87, 2.13, and 1.63 for glomerular filtration rate categories G3a, G3b, G4, and G5/G5D, respectively.

Study details: The data come from a retrospective cohort study of 12,618 adults.

Disclosures: The study was supported by the National Institutes of Health and the American Society of Nephrology. The researchers had no financial conflicts to disclose.


Edmonston DL et al. Am J Kidney Dis. 2019;75:713-24.