Clinical Edge

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Regular Use of Disinfectants at Work Associated With Increased Risk of COPD

Key clinical point: Occupational use of disinfectants and cleaning products may increase long-term risk of developing chronic obstructive pulmonary disease.

Major finding: Weekly use of disinfectants was associated with COPD incidence (adjusted hazard ratio, 1.35; 95% confidence interval, 1.14-1.59).

Study details: A prospective cohort study of 73,262 female nurses who were occupationally exposed to cleaning products and disinfectants.

Disclosures: The study was supported in part by grants from the Centers for Disease Control and Prevention and the National Institutes of Health. Five of the authors reported receiving grants from the CDC’s National Institute for Occupational Safety and Health (NIOSH); one additional author reported being a consultant on a NIOSH grant and receiving personal fees from a health care system. No other conflicts of interest were reported.


Dumas O et al. JAMA Netw Open. 2019 Oct 18. doi: 10.1001/jamanetworkopen.2019.13563.