Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Urbanicity, Psychosis, and Developing Countries

JAMA Psychiatry; ePub 2018 May 16; DeVylder, et al

Urbanicity, a well-established risk factor for psychosis, may not be associated with elevated odds for psychosis in developing countries, according to a recent study. This international population-based study used cross-sectional survey data collected as part of the World Health Organization (WHO) World Health Survey from May 2, 2002, through December 31, 2004. Participants included nationally representative general population probability samples of adults (≥18 years) residing in 42 low- and middle-income countries (LMICs) (n=215,682). Researchers found:

  • Among total participants (50.8% women and 49.2% men; mean [SD] age, 37.9 [15.7] years), urban residence was not associated with psychotic experiences or psychotic disorder.
  • Results of all pooled analyses and meta-analyses of within-country effects approached a null effect, with overall odds ratio (OR) of 0.97, OR for low-income countries of 0.98, and OR for middle-income countries of 0.96 for psychotic experiences, and an overall OR of 0.92, OR for low-income countries of 0.92, and OR for middle-income countries of 0.92 for psychotic disorder.

Citation:

DeVylder JE, Kelleher I, Lalane M, Link BG, Koyanagi A. Association of urbanicity with psychosis in low- and middle-income countries. [Published online ahead of print May 16, 2018]. JAMA Psychiatry. doi:10.1001/jamapsychiatry.2018.0577.

This Week's Must Reads

Reduced Lateral OFC Volume and Suicidality in BD, Bipolar Disord; ePub 2018 Nov 24; Huber, et al

Subthreshold Pediatric BD Linked with Suicide Risk, Bipolar Disord; ePub 2018 Nov 27; Vaudreuil, et al

Mood Symptoms and Suicidality in Bipolar Disorder, Suicide Life Threat Behav; ePub 2018 Nov 19; Kamali, et al

Smokers with BD and Quit Rates Examined, Drug Alcohol Depend; 2018 Dec 1; Heffner, et al

Determining Objective Chronotype in Persons with BD, J Affect Disord; 2018 Dec; Kaufmann, et al

Must Reads in Schizophrenia & Other Psychotic Disorders

Predictors of Social Functioning in Schizophrenia, Schizophr Res; ePub 2018 Nov 13; Harvey, et al

Insomnia, Suicide Ideation in Schizophrenia Linked, Sleep; ePub 2018 Nov 8; Miller, Parker, et al

Psychotic-Like Experiences and Cannabis Use, JAMA Psychiatry; ePub 2018 Oct 17; Karcher, et al

Women with Schizophrenia Have Poor Sleep Quality, Am J Geriatr Psych; ePub 2018 Oct 11; Lee, et al

Cognitive Deterioration in Schizophrenia Examined , JAMA Psychiatry; ePub 2018 Oct 3; Niendam, et al