Urbanicity, a well-established risk factor for psychosis, may not be associated with elevated odds for psychosis in developing countries, according to a recent study. This international population-based study used cross-sectional survey data collected as part of the World Health Organization (WHO) World Health Survey from May 2, 2002, through December 31, 2004. Participants included nationally representative general population probability samples of adults (≥18 years) residing in 42 low- and middle-income countries (LMICs) (n=215,682). Researchers found:
- Among total participants (50.8% women and 49.2% men; mean [SD] age, 37.9 [15.7] years), urban residence was not associated with psychotic experiences or psychotic disorder.
- Results of all pooled analyses and meta-analyses of within-country effects approached a null effect, with overall odds ratio (OR) of 0.97, OR for low-income countries of 0.98, and OR for middle-income countries of 0.96 for psychotic experiences, and an overall OR of 0.92, OR for low-income countries of 0.92, and OR for middle-income countries of 0.92 for psychotic disorder.
DeVylder JE, Kelleher I, Lalane M, Link BG, Koyanagi A. Association of urbanicity with psychosis in low- and middle-income countries. [Published online ahead of print May 16, 2018]. JAMA Psychiatry. doi:10.1001/jamapsychiatry.2018.0577.
This Week's Must Reads
Depression May Be Linked with SLE Risk in Women, JAMA Psychiatry; ePub 2018 Sep 12; Roberts, et al
Women with MDD During the Childbearing Years, Depress Anxiety; ePub 2018 Sep 7; Freeman, et al
Resilience Examined in Older Adults with Depression, Am J Geriatr Psychiatry; ePub 2018 Aug 25; Laird, et al
Disparities in Depression Care Among Arab Americans, Depress Anxiety; ePub 2018 Aug 12; Dallo, et al
Telehealth vs In-Person Care for Depressed Veterans, J Clin Psychiatry; 2018 Aug 28; Egede, et al
Must Reads in Schizophrenia & Other Psychotic Disorders
FDA Approves Perseris for Schizophrenia, FDA news release; 2018 Jul 27
Gender Differences in Schizophrenia May Vary by Age, Am J Geriatr Psychiatry; ePub 2018 Jul 27; Muralidharan, et al
Folic Acid Exposure Linked with Psychosis Reduction, JAMA Psychiatry; ePub 2018 Jul 3; Eryilmaz, et al
FDA Approves New Dosing Formulation for Nuplazid, Acadia Pharmaceuticals Inc. news release; 2018 Jun 29
FDA Approves Initiation Drug for Schizophrenia, Alkermes plc news release; 2018 Jul 2