Urbanicity, a well-established risk factor for psychosis, may not be associated with elevated odds for psychosis in developing countries, according to a recent study. This international population-based study used cross-sectional survey data collected as part of the World Health Organization (WHO) World Health Survey from May 2, 2002, through December 31, 2004. Participants included nationally representative general population probability samples of adults (≥18 years) residing in 42 low- and middle-income countries (LMICs) (n=215,682). Researchers found:
- Among total participants (50.8% women and 49.2% men; mean [SD] age, 37.9 [15.7] years), urban residence was not associated with psychotic experiences or psychotic disorder.
- Results of all pooled analyses and meta-analyses of within-country effects approached a null effect, with overall odds ratio (OR) of 0.97, OR for low-income countries of 0.98, and OR for middle-income countries of 0.96 for psychotic experiences, and an overall OR of 0.92, OR for low-income countries of 0.92, and OR for middle-income countries of 0.92 for psychotic disorder.
DeVylder JE, Kelleher I, Lalane M, Link BG, Koyanagi A. Association of urbanicity with psychosis in low- and middle-income countries. [Published online ahead of print May 16, 2018]. JAMA Psychiatry. doi:10.1001/jamapsychiatry.2018.0577.
This Week's Must Reads
Early-Life Stress Linked with Cytomegalovirus in MDD , JAMA Psychiatry; ePub 2019 Mar 6; Ford, et al
Collaborative Intervention for Obesity, Depression , JAMA; 2019 Mar 5; Ma, Goldman Rosas, Lv, et al
Body Weight Predicts Risk for Depressive Symptoms , J Affect Disord; ePub 2019 Mar 5; Vittengl
Slow-Wave Activity and Mood Disturbance in MDD, Psychol Med; 2019 Mar; Goldschmied, et al
Marijuana Use in MDD May Be Contraindicated, Cogn Affect Behav Neurosci; ePub 2019 Feb 26; Radoman, et al
Must Reads in Schizophrenia & Other Psychotic Disorders
Comparing Effectiveness of Psychotropic Medications , JAMA Psychiatry; ePub 2019 Feb 20; Stroup, et al
Link Between GM Measures and Symptom Dimensions, Schizophr Res; ePub 2019 Feb 26; Mennigen, et al
Assessment of 3-Dimensional Wisdom in Schizophrenia, Schizophr Res; ePub 2019 Feb 14; Van Patten, et al
Racial Diagnostic Bias of Schizophrenia Explored, J Abnorm Psychol; ePub 2019 Feb 14; Schwartz, et al
Diffusion Abnormalities in the Corpus Callosum , Psychiatry Res; ePub 2019 Feb 18; del Re, et al