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Schizophrenia: Niacin skin flush response linked to plasma triglyceride levels

Key clinical point: Niacin-induced skin flushing is positively and strongly associated with plasma triglyceride levels in patients with schizophrenia.

Major finding: Higher total volumetric niacin response (VNR) values were significantly associated with higher plasma triglyceride levels in patients with schizophrenia and total VNR accounted for approximately 14% of the variability in triglyceride levels (P=.004).

Study details: Study evaluated the association between the skin flush response to niacin and lipid and glucose metabolism in patients with schizophrenia (n=78).

Disclosure: This study was supported by grants from the University of Rijeka, Croatia. The authors declared no conflicts of interest.


Nadalin S et al. Prostaglandins Leukot Essent Fatty Acids. 2020 Feb 21. doi: .4088/JCP.19m12769.