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Schizophrenia and sexual dysfunction: Is there a link?

Key clinical point: The rates of sexual dysfunction events are higher in both men and women with schizophrenia compared with the general population.

Major finding: Pooled data revealed increased rates of sexual dysfunction in patients with schizophrenia vs. the general population (for both sexes: 3 studies, 49.7% vs. 22.2%; relative risk [RR], 2.24). For men with schizophrenia (7 studies, 57.4% vs 23.1%; RR, 2.63) and for women (5 studies, 60.9% vs 37.7%; RR, 2.07).

Study details: Meta-analysis of 10 observational studies including 3,570 patients, of whom 1,161 had schizophrenia.

Disclosures: No study sponsor was identified. The authors declared no conflicts of interest.


Zhao S et al. J Sex Med. 2020 Apr 13. doi: 10.1016/j.jsxm.2020.03.005.