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Racial-ethnic Disparities and Psychosis

Evidence seen in subthreshold subtypes

There was evidence of racial-ethnic disparities in subthreshold psychosis subtypes in a study involving 6,533 individuals ranging from 11 to 21 years of age.

Investigators formed subtypes of subpsychosis based on 12 attenuated positive items and 7 mania items. They looked for links between race-ethnicity and subpsychosis subtype using latent class regression.

Among the results:

• 4 classes were identified: Sub-positive only (13.4%), mania only (15.5%), both (9.1%), and neither (62.0%).

• Minority participants were more likely than whites to belong to one of the three sub-psychosis classes compared to the neither class.

• This remained the case for Hispanics and blacks after adjusting for demographic variables and limiting analysis to participants without significant physical health conditions.

• Racial-ethnic disparities were greater for the sub-positive only and both groups than they were for mania only; this pattern was statistically significant among blacks.

Citation: Paksarian D, Merikangas K, Calkins M, Guy R. Racial-ethnic disparities in empirically-derived subtypes of subclinical psychosis among a U.S. sample of youths. [Published online ahead of print December 17, 2015]. Schizophr Res. doi: http://dx.doi.org/10.1016/j.schres.2015.12.004.