Key clinical point: In adults with schizophrenia, deficits in phonological reading ability predict worse functional capacity, and deficits in reading fluency predict impairment in functional capacity and functional outcome as measured by the UCSD Performance-based Skills Assessment and Specific Level of Functioning scale.
Major finding: Adults with schizophrenia showed significant deficits in phonological processing and reading fluency, compared with controls (P = 0.009 and P less than 0.00005, respectively). However, single word reading skills among adults with schizophrenia were not significantly different, compared with controls.
Study details: The data come from a study of 30 adults with schizophrenia and 28 matched controls.
Disclosures: Clément Dondé, MD, PhD, had no financial conflicts to disclose. The study was supported by the National Institutes of Mental Health, the Brain & Behavior Research Foundation, the American Psychiatric Foundation, the Sydney J. Baer Foundation, the Leon Levy Foundation, and the Herb and Isabel Stusser Foundation.
Dondé C et al. Sci Rep. 2019. doi: 10.1038/s41598-019-52669-6.