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Correlates of Future Violence in Schizophrenia

In a large cohort of patients with schizophrenia, simultaneous strong effects of baseline injurious violence and recent violent victimization on future injurious violent behavior were revealed. The study included 1,435 individuals with schizophrenia who participated in the National Institute of Mental Health’s Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study. They were followed for 18 months. The dependent variables were self-reported injurious and noninjurious violence during follow-up. Researchers found:

  • 5.4% of participants reported engaging in injurious violence during follow-up, and 8.3% reported engaging in exclusively noninjurious violence.
  • Among clinical variables, poor medication adherence, but not baseline symptoms of psychosis or depression, significantly predicted injurious violence.


Buchanan A, et al. Correlates of future violence in people being treated for schizophrenia. [Published online ahead of print April 24, 2019]. Am J Psychiatry. doi:10.1176/appi.ajp.2019.18080909.