Clinical Edge

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Medications may drive postmenopausal weight gain

Key clinical point: Postmenopausal women who use weight-promoting medications gained significantly more weight than did women not on such medications.

Major finding: During a 3-year follow-up period, women taking at least one weight-promoting medication increased their body mass index by an average of 0.37 kg/m2 versus 0.27 kg/m2 in women not taking such medications.

Study details: The data come from a prospective, observational cohort study of 76,252 postmenopausal women as part of the Women’s Health Initiative.

Disclosures: The study was supported by the National Institutes of Health and Massachusetts General Hospital Executive Committee on Research, the National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases. The researchers had no financial conflicts to disclose.


Stanford FC et al. Menopause. 2020 Jul 13. doi: 10.1097/GME.0000000000001589.