Clinical Edge

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MDD: Recognition of comorbid alcohol use disorder is important

Key clinical point: Among patients with major depressive disorder (MDD), comorbid alcohol use disorder is more common in male patients and smokers and associated with other mental disorders.

Major finding: In patients with MDD, the comorbid alcohol use disorder was associated with male sex (odds ratio [OR], 3.91; P less than .001), panic disorder (OR, 3.52; P = .005), daily smoking (OR, 3.97; P less than .001), suicidal ideation (OR, 1.06; P = .007), and the number of any personality disorder symptoms (OR, 1.04; P = .035).

Study details: The Vantaa Depression Study was a prospective long-term study of psychiatric out- and inpatients with MDD (follow-up, 5 years; n = 269).

Disclosures: No external funding. The authors declared no conflicts of interest.


Holma M et al. J Affect Disord. 2020 Apr 15. doi: 10.1016/j.jad.2020.02.024.