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Can LDAEP Reveal Adult ADHD Symptoms in MDD?

Loudness dependence of auditory evoked potential (LDAEP) can reflect adult attention deficit and hyperactivity disorder (ADHD) symptoms in major depressive disorder (MDD), a new study suggests. 60 participants (40 subjects with MDD and 20 healthy controls) aged >18 years who had LDAEPs performed during electroencephalograms were included. ADHD symptoms, depressive symptoms, and anxiety symptoms were evaluated. Researchers found:

  • MDD subjects with ADHD symptoms shoed significantly lower LDAEP levels compare to those without ADHD symptoms and healthy controls.
  • LDAEP differences between MDD subjects without ADHD symptoms and healthy controls was not statistically significant.
  • Significant correlations of psychological scales of depression, ADHD symptoms, and LDAEPs were found.


Kim JS, et al. The relationship between auditory evoked potentials and symptoms of attention-deficit/hyperactivity disorder in adult patients with major depressive disorder. [Published online ahead of print June 14, 2019]. Int J Psychophysiol. doi: 10.1016/j.ijpsycho.2019.06.008.