Gender differences among adults with schizophrenia may vary depending on age, according to a recent study. In addition, gender differences on negative symptoms may vary by symptom subgroup. Community-dwelling adults (n=242, aged 40-85) with schizophrenia/schizoaffective disorder completed assessments of negative symptoms (expressive and experiential deficits), neurocognition, and social skills. Mann-Whitney U tests examined gender differences; a regression-based bootstrapped approach to moderation examined gender by age interactions. Researchers found:
- Female participants had better neurocognition (U= 6,814.00) and less severe experiential deficits (U=4,130.50).
- There was no gender difference on social skills (U=5,920.50).
- Older age was associated with greater expressive deficits among men but not women (b= -.04).
Muralidharan A, Harvey PD, Bowie CR. Associations of age and gender with negative symptom factors and functioning among middle-aged and older adults with schizophrenia. [Published online ahead of print July 27, 2018]. Am J Geriatr Psychiatry. doi:10.1016/j.jagp.2018.07.006.
This Week's Must Reads
Early-Life Stress Linked with Cytomegalovirus in MDD , JAMA Psychiatry; ePub 2019 Mar 6; Ford, et al
Collaborative Intervention for Obesity, Depression , JAMA; 2019 Mar 5; Ma, Goldman Rosas, Lv, et al
Body Weight Predicts Risk for Depressive Symptoms , J Affect Disord; ePub 2019 Mar 5; Vittengl
Slow-Wave Activity and Mood Disturbance in MDD, Psychol Med; 2019 Mar; Goldschmied, et al
Marijuana Use in MDD May Be Contraindicated, Cogn Affect Behav Neurosci; ePub 2019 Feb 26; Radoman, et al
Must Reads in Geriatrics
Disparities in Receipt of ECT in Depressed Elderly, Am J Geriatr Psychiatry; ePub 2018 Nov 29; Jones, et al
Depression in Later Life Intervention is Effective, JAMA Psychiatry; ePub 2018 Nov 7; Dias, et al
More than One-Third of Older Adults Use Sleep Aids, Am J Geriatr Psychiatry; ePub 2018 Sep 14; Maust, et al
Older Adults and Worry: Which Treatments Work Best?, Am J Geriatr Psych; ePub 2018 Aug 7; Stanley, et al
Gender Differences in Schizophrenia May Vary by Age, Am J Geriatr Psychiatry; ePub 2018 Jul 27; Muralidharan, et al