Clinical Edge

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Most CBT delivery methods effective for depression

Key clinical point: Regardless of the delivery method, most forms of cognitive-behavioral therapy are effective for improving the severity of depression.

Major finding: Individual, group, telephone, and guided self-help cognitive-behavioral therapy all achieve significant improvements in depression, compared with controls.

Study details: A network meta-analysis of 155 trials involving 15,191 participants.

Disclosures: Two authors reported receiving personal fees from private industry outside of the submitted work, and one reported receiving grants and support from the National Institute for Health Research.


Cuijpers P et al. JAMA Psychiatry. 2019 Apr 17. doi: 10.1001/jamapsychiatry.2019.0268.